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The most active coumarin-based anticoagulant rodenticide ideal to keep larger pests such as possum at bay.


This is the most sought after 2nd-generation anticoagulant rodenticide with a simple 4-step procedure coumarin derivative.


This has the same synthesis steps as Brodifacoum, original absent actives ‘Br’, it is safer for ecology especially birds.


On February 8, 2017, China State Council approved the amendment to the “Regulation on the Administration of Pesticides” – Decree No. 677, while repealing Decree No. 326 of 2001. This is the third amendment since the first regulation, Decree No. 216 was enacted the year 1997.

On June 21, 2017,  Ministry of Agriculture (MOA) issued “The Measures for the Administration of the Pesticide Registration (2017)” under the State Decree No. 677, it shall come into force on August 1, 2017. – MOA Order No.3/2017.

On August 31, 2017, China MOA issued Proclamation No. 2567 under the latest 2017 Food Safety Law, the “List of Restricted Use Pesticides (2017)” including 32 pesticides, it will come into force as of November 1, 2017.


The current 6 valid registrations of rodenticide active ingredients in China MOA (Flocoumafen, Sodium Diphacinone, Warfarin, Coumatetralyl, Bromadiolone, Brodifacoum) have been included into the “List of Restricted Pesticides” of year 2017.  All of them will subject to production at the traceable ‘designated site’ and designation marketing management such as ID-based purchase and controlled retailers, etc.

In fact, with the exception of the national Brodifacoum and Bromadiolone, the production of other 4 registered actives have never been approved as ‘designated site’ by MIIT (Ministry of Industry and Information Technology) and is therefore no meaning in the above list.


In the last three decades, several companies have registered various rodenticides in China MOA, but the MIIT has so far approved the industrial synthesis of 2 rodenticide active ingredients, which are, Brodifacoum and Bromadiolone, at only 2 designated sites under the safety laws and environmental regulations. According to the Article 40 of 2017 Pesticide Registration Regulation, all MOA registrations without production designated will be invalid with effect on August 1, 2019.

In short, after 2019, China has only 2 rodenticide technical active ingredients are valid, Brodifacoum and Bromadiolone, while the 2 designated manufacturers are the only legal sellers.

This is similar to the change from BPD (Directive 98/8/EC) to BPR (EU 528/2012) and the Article 95 list which is enforced in the EU countries. This is always known as ‘designated site’ in China, a direct translation based on the Chinese language.


Siyang Rodenticide Factory was established in 1985 as a state designated rodenticide production unit approved by the former Ministry of Chemical Industry.

Siyang Rodenticide Factory is currently a designated Rodenticide Technical Material Manufacturer approved by MIIT (the former Ministry of Chemical Industry).

Siyang Rodenticide Factory is mainly supplying Brodifacoum Technical, Bromadiolone Technical and the last Intermediate of Difenacoum.


In 2005, Siyang Rodenticide Factory participated in the review meeting for China’s National Rodenticide held by MOA. It’s the final conclusion on Chinese rodenticides under the 2005 National Industrial Policy.

  • In 2006, AQSIQ and SAC jointly enacted China’s National Standard – GB (GuoBiao) for Bromadiolone Technical Material (GB 20678-2006) and Brodifacoum Technical Material (GB 20690-2006).

  • In 2008, Siyang Rodenticide Factory was issued the National Industrial Production Permit by AQSIQ for MOA registrations of Brodifacoum TC 98% and Bromadiolone TC 98%.

  • In 2013, Siyang Rodenticide Factory obtained the renewed National Industrial Production Permit of Brodifacoum TC and Bromadiolone TC with the License No. XK13-003-00347.

  • In 2019, Siyang Rodenticide Factory was officially issued the NEW Pesticide Business License (Restricted Class) in accordance with 2017 Pesticide Regulations with the Unique Number for Administration of Pesticide: (SU) 32000010534.