Brodifacoum TC ≥ 98% | Bromadiolone TC ≥ 98%

Brodifacoum, Brodifacoum manufacturer in China

BRODIFACOUM TC

Brodifacoum Technical Material, 98% Reg.
MOA’s Reg. No.: PD20070323 (Pesticide only)
Extreme Toxic Chemicals Permit (Operation)
Restricted Pesticide License (Market/Export)
UN3027, Class 6.1, PG: I. (Steel Packaging)
China Tariff No.: 2932209011 (Legislated)
The most potent ‘super-warfarin’ rodenticide, ideal for controlling larger pests, features a complex 8-step synthesis process.

BROMADIOLONE TC

Bromadiolone Technical Material, 98% Reg.
MOA’s Reg. No.: PD20070322 (Pesticide only)
Extreme Toxic Chemicals Permit (Operation)
Restricted Pesticide License (Market/Export)
UN3027, Class 6.1, PG: I. (Steel Packaging)
China Tariff No.: 2932209013 (Legislated)
The most widely used 2nd-generation anticoagulant rodenticide, a 4-step manufactured coumarin derivative.

DIFENACOUM STAGE 6

C₂₂H₂₀O (CAS# 56181-66-9), Purity ≥ 99.7%
Since the 2005 Industrial Decree (now 2024 version), China has prohibited the production of new rodenticide active substances, including Difenacoum. We used to have an approved production line that manufactured and stocked some intermediates for export.
Synthesized in the same manner as Brodifacoum without the Bromine in initiation, ecologically safer for birds.

Extremely Toxic Chemicals License since 2002

(now updated to 2015 version)

(Hazardous Substance List: #2413 Brodifacoum, #2414 Bromadiolone)

Substances exported as hazardous chemicals are subject to the supervision of the Maritime Administration – Compliant with “UN3027, Class 6.1, PG: I.”

The “2015 Extremely Toxic Chemicals Directory” is derived from the list of Extremely Toxic Chemicals identified in the “Catalogue of Hazardous Chemicals (2015 Edition)” (current standard) formulated by the State Administration of Work Safety of the People’s Republic of China (SAWS) and other relevant departments. Compared to the 2002 edition of the “Extremely Toxic Chemicals Directory,” the criteria for determining extremely toxic chemicals have changed. For example, in the 2002 edition of the Directory, the LD₅₀ (rat oral) standard was ≤50 mg/kg, while in the 2015 edition, it has been revised to ≤5 mg/kg.
(https://www.mem.gov.cn/gk/zcjd/201503/t20150331_233183.shtml)
Brodifacoum (Hazardous Material Number 2413, labeled as “extremely toxic”) and Bromadiolone (Hazardous Material Number 2414, labeled as “extremely toxic”) are China’s highest-level controlled hazardous substances. The two main regulatory agencies are: the former SAWS, the State Administration of Work Safety, now MEM, the Ministry of Emergency Management and the Ministry of Public Security (since the 2005 regulation).
(https://www.gov.cn/zhengce/2021-12/25/content_5712923.htm)
(https://www.mem.gov.cn/gk/gwgg/xgxywj/wxhxp_228/201509/t20150902_232638.shtml)
August 19, 2015, SAWS issued a guidance document containing the official GHS classification of chemicals listed in the Directory.
(https://www.mem.gov.cn/gk/gwgg/xgxywj/wxhxp_228/201509/W020171030616953518195.doc)
New Extremely Toxic License issued by MEM (former SAWS Hazardous License)
Since 2002, in accordance with the above regulations, the production and sale of Bromadiolone TC and Brodifacoum TC in China has been included in the scope of mandatory hazardous chemical license management and is reviewed and approved by SAWS. In 2018, SAWS was merged into the newly established Ministry of Emergency Management (MEM). In 2021, our factory’s new relocation passed the MEM department inspection and was awarded an updated extremely toxic chemical license.
(https://en.wikipedia.org/wiki/State_Administration_of_Work_Safety)
(https://en.wikipedia.org/wiki/Ministry_of_Emergency_Management)
Please note that since 2002, China has only issued two licenses, one to us and one to Tianjin. Therefore, apart from these two licenses, all production and sales of brodifacoum and bromadiolone active substances within China, including export trade, have been illegal.
Official website for querying and verifying Hazardous Chemical Permits:
(https://whjy.mem.gov.cn/#/licenseSearch)
Latest update: Siyang Rodenticide Factory completed the renewal of its new MEM Extremely Toxic Chemical Permit (Brodifacoum TC and Bromadiolone TC) on 24/JUNE/2024, which is valid until 23/JUNE/2027.
Screenshot of the verification results from the Siyang Rodenticide Factory:
(https://www.rodenticide.com.cn/wp-content/uploads/2025/07/hazardous.jpg)

‘National Industrial Regulations’ since 2005

(the catalog updated to 2024)

Prohibition of the production of all New rodenticide active ingredients and New producers

Dec. 2, 2005, China’s National Industrial Regulations launched – the Decision of the State Council on Promulgating the “Interim Provisions on Promoting Industrial Structure Adjustment” for Implementation (the No. 40 [2005] of the State Council).
(Official link: https://www.gov.cn/zwgk/2005-12/21/content_133214.htm)

– The “Directory for Guiding Industry Restructuring (2005 Edition)” (now updated to the 2024 Edition) is a detailed catalog directive under the 2005 Industrial Regulation. The catalog stipulates that highly toxic pesticide rodenticides are classified as restricted industrial projects, meaning that only existing qualifications will be retained, new developments will be prohibited, all new active ingredients and new manufacturers will no longer be approved. The catalog lists in detail all rodenticide varieties registered in China, including “Warfarin, Coumatetralyl, Bromadiolone and Brodifacoum, etc.”
Official link: (Category II: Restricted, Paragraph 4, Section 37)
(https://www.ndrc.gov.cn/xxgk/zcfb/fzggwl/200512/t20051222_960679.html)

– “Directory for Guiding Industry Restructuring (2011 edition)”
Official link: (Category II: Restricted, Page 66 and 67)
(https://www.gov.cn/gzdt/att/att/site1/20110426/001e3741a2cc0f20bacd01.pdf)

– “Directory for Guiding Industry Restructuring (2019 edition)”
Official link: (Category II: Restricted, Paragraph 4, Section 8)
(https://www.gov.cn/zhengce/2021-12/27/content_5713262.htm)

– “Directory for Guiding Industry Restructuring (2024 edition)”
Official link: (Category II: Restricted, Page 88):
(https://www.ndrc.gov.cn/xxgk/zcfb/fzggwl/202312/P020231229700886191069.pdf)

ICAMA Registration: Brodifacoum Technical 98%

ICAMA Registration: Bromadiolone Technical 98%

Difenacoum Intermediate ≥ 99% | C₂₂H₂₀O

China’s strictest pesticide rodenticide production license

(1997 – 2007 – 2017)

Brodifacoum and Bromadiolone officially became National Rodenticides in 2007, and as such pesticides production in China is subject to the issuance of a production license by the AQSIQ, which has been taken over by the MOA since the new pesticide law in 2017.

The export of commercial pesticides is jointly regulated by the MOA and Customs. The legislated tariff number for pesticides Brodifacoum TC/TK is “2932209011”, and for Bromadiolone TC/TK is “2932209013”.

Siyang Rodenticide Factory is State – “Designated-Site Rodenticide Plant”. The “designated-site”, a direct translation from Mandarin, in fact, it refers to the pesticide rodenticide that is really produced in China with full qualification, which is approved by three ministries and commissions in turn, and ultimately obtains the AQSIQ production license:
✔ (1) First of all, since 1997, China’s pesticide management regulations are implemented, rodenticide as a commercial pesticide must be registered in the MOA;
✔ (2) Secondly, as a manufacturer of pesticide technical materials, the environmental and safety evaluation of its production sites needs to be reviewed and approved by NDRC, the National Development and Reform Commission.
✔ (3) Since the implementation of the national standards for Brodifacoum and Bromadiolone in 2007, rodenticides have become official pesticide products at the national level. So after completing the above two qualifications, the final authorization of production permit is carried out by AQSIQ, the General Administration of Quality Supervision, Inspection and Quarantine of the People’s Republic of China.
China’s AQSIQ finally approved the production of two rodenticide active ingredients, Brodifacoum and Bromadiolone, by two production sites designated (our Siyang County and Tianjin City) by the National Development and Reform Commission (NDRC) as complying with national standards.
Since 2008, the renewal of NDRC-designated production sites has been taken over by the Ministry of Industry and Information Technology (MIIT). This is because the NDRC banned new production sites after 2005 and they have completed their historical mission of approving the production of rodenticides in China.
From 2017, under the new pesticide law, MOA took over the renewal of designated sites from the Ministry of Industry and Information Technology (MIIT), and also took over the renewal of production certificates from AQSIQ (now State Administration for Market Regulation). It also marks the completion of China’s pesticide industrial revolution after more than two decades of development and reform.

The new Pesticide Law of 2017

Regulation on Pesticide Administration
On Feb. 8, 2017, the State Council of China approved an amendment to the “Regulation on the Administration of Pesticides” – known as the State Decree No. 677, coinciding with repeal of the 2001 State Decree No. 326.
(https://www.gov.cn/gongbao/content/2017/content_5186961.htm)
List of Restricted Pesticides (2017 Edition)
On August 31, 2017, the Ministry of Agriculture (MOA) of China issued Announcement No. 2567, “List of Restricted-Use Pesticides,” which included a total of 32 pesticides. Among these, 22 pesticides are subject to “designated-site sales,” including four coumarin-based rodenticides: “Warfarin (No. 19), Coumatetralyl (No. 20), Bromadiolone (No. 21), and Brodifacoum (No. 22).”
(http://www.moa.gov.cn/nybgb/2017/dsq/201802/t20180201_6136189.htm)
February 1, 2019: Siyang Rodenticide Factory passed the new “designated site” of restricted pestides review by the MOA (previously handled by the AQSIQ) and obtained a new restricted pesticide license.
– Latest update: In September 2021, Siyang Rodenticide Factory was relocated and the new site was granted a new MOA Restricted Pesticide License (Su) 32000013199, which is valid until 14/Sep./2026.
(http://nynct.jiangsu.gov.cn/art/2025/3/19/art_80243_11352.html)

New export administration measures updated under

the 2015 Hazardous Chemicals Regulation and the 2017 Pesticides Regulation

The General Administration of Customs (GAC)

In 2018, AQSIQ merged with the newly established State Administration of Market Supervision (SAMR). At the same time, the AQSIQ’s entry-exit inspection and quarantine (well known CIQ, the “China Inspection and Quarantine”) management responsibilities and teams were transferred to the General Administration of Customs (GAC).
(https://en.wikipedia.org/wiki/General_Administration_of_Quality_Supervision,_Inspection_and_Quarantine)
(https://en.wikipedia.org/wiki/State_Administration_for_Market_Regulation)
(http://www.customs.gov.cn/customs/ztzl86/302414/302415/zl70zn_fdxsd/2566516/2585161/index.html)
Dec 18, 2020: The China GAC issued an Announcement No. 129 under the State Council Decree No. 591 (“2011 Hazardous Chemical Regulation”) and the “2015 Hazardous Chemicals List”, repealing AQSIQ Announcement No. 30 of 2012. Mandatory inspection of imports and exports of hazardous chemicals listed in the “2015 Hazardous Chemicals List”, the measures including hazard classification certification, qualified UN GHS labeling and data, UN TDG required packaging, etc. There are 28 pesticides in the new “2015 Hazardous Chemicals List”, including three coumarin-based rodenticides as “Warfarin, Brodifacoum and Bromadiolone”.
(http://www.customs.gov.cn/customs/302249/302266/302267/3476363/index.html)
Dec 31, 2021, In order to implement the obligations of the Rotterdam Convention, the GAC and the MOA jointly issued “Announcement the No. 416” in accordance with the “Chinese Customs Law” and the “Regulation on Pesticide Administration (2017)”.
(http://www.customs.gov.cn/customs/ztzl86/302414/302415/zl70zn_fdxsd/2566516/2585161/index.html)
The implementation of electronic customs clearance for import and export of pesticides. The latest 2022 version of the “Catalogue of the People’s Republic of China for the Administration of the Import and Export of Pesticides” was also released, with the total number of pesticides increased from 1,183 to 1,238. The tariff number for pesticide export number 645, “Brodifacoum,” is 2932209011, and the tariff number for pesticide export number 640, “Bromadiolone,” is 2932209013. These two tariff numbers remain unchanged.
(https://www.gov.cn/zhengce/zhengceku/2021-12/31/5665804/files/a690fececdf44b9aba505e6e40bb19ae.doc)

Siyang Rodenticide Factory is the only licensed exporter of Brodifacoum TC and Bromadiolone TC in China

– based on the 2015 Hazardous Chemicals Regulations and the 2017 Pesticides Act.

Since obtaining export qualifications in 2006, Siyang Rodenticide Factory has been the sole legal exporter of Brodifacoum TC and Bromadiolone TC within China. Currently, the legal procedures for compliant export are as follows (three mandatory certifications):

“Hazard Classification Certificate” – (Certification: Valid only for the current year):
the classification of hazardous chemicals (Bromadiolone TC, Brodifacoum TC) will be certified as “UN3027, Class:6.1, PG: I” with reference to “UN TDG Regulation” (United Nations Recommendations on the Transport of Dangerous Goods – UN Model Regulations, Rev. 23 (2023)).
(Official Link: https://unece.org/transport/dangerous-goods/un-model-regulations-rev-23)
“Syndrome of dangerous package/Dangerous Goods Certificate” – (Certification: The validity period of export packaging is only 12 months):
The export of bromadiolone and brodifacoum is subject to mandatory GAC inspection (formerly CIQ inspection). The certified TDG hazard classification, comply with the provisions of the International Maritime Dangerous Goods Code (IMDG Code), and meet the requirements of the Globally Harmonized System of Classification and Labelling of Chemicals (UN GHS) or the EU CLP (Regulation (EC) No 1272/2008).
(https://www.mem.gov.cn/gk/gwgg/xgxywj/wxhxp_228/201509/t20150902_232638.shtml)
(http://www.customs.gov.cn/customs/ztzl86/302414/302415/zl70zn_fdxsd/2566516/2585161/index.html)
“Pesticide Export Release Certificate” – (Certification: Valid for only 3 months from the date of issuance):
The export release certificate for Chinese pesticides is issued by the MOA, and the export tariffs codes “2932209011 (Brodifacoum)” and “2932209013 (Bromadiolone)” have been included in the relevant Chinese pesticide management regulations (the “Catalogue of the People’s Republic of China for the Administration of the Import and Export of Pesticides,” currently the 2022 edition).
(https://www.gov.cn/zhengce/zhengceku/2021-12/31/5665804/files/a690fececdf44b9aba505e6e40bb19ae.doc)

Siyang Rodenticide Factory

2025: 40th Anniversary

Siyang Rodenticide Factory, as the name implies, is a professional rodenticide manufacturing plant located in Siyang County, China. It was established in March 1985.

A leading pioneer in rodenticides in China, successfully industrializing the synthesis of six anticoagulant rodenticides: “Chlorophacinone, Warfarin, Coumatetralyl, Bromadiolone, Brodifacoum and Difenacoum.”

Under China’s latest regulatory reform in 2017, Siyang Rodenticide Factory is now defined as a “designated site of Restricted-Pesticide” by the MOA for supply of Bromadiolone and Brodifacoum.

Two national rodenticides in China

Brodifacoum, Bromadiolone

In 2005, Siyang Rodenticide Factory participated in the Review Meeting of Rodenticides in China held by the ICAMA (Institute for the Control of Agrochemicals, MOA): Brodifacoum and Bromadiolone were adopted as official rodenticides in China.

In 2006, China SAC and AQSIQ jointly enacted national standards (GB) for Brodifacoum and Bromadiolone, which came into effect in 2007.

Regulatory Reform of Rodenticides in China

In 1997, China promulgated its first pesticide management regulations.
Administrative authorities: ICAMA (Institute for the Control of Agrochemicals, MOA).
In 2002, China promulgated its first Regulations on the Safety Management of Hazardous Chemicals and a List of Extremely Toxic Chemicals.
Administrative authorities: (SAWS) State Administration of Work Safety.

In 2005, China promulgated the National Industrial Law, along with detailed Regulations.

Administrative authorities: (NDRC) National Development and Reform Commission, replaced by (MIIT) the Ministry of Industry and Information Technology after the promulgation of national standards in 2006.
In 2005, the Ministry of Public Security promulgated the Measures for the Administration of Permits for the Purchase and Road Transportation of Extremely Toxic Chemicals.

Administrative authorities: (MPS) Ministry of Public Security.
In 2007, National Standards (China’s GB) for Bromadiolone and Brodifacoum were introduced.

Administrative authorities: (AQSIQ) General Administration of Quality Supervision, Inspection and Quarantine, now (GAC) the General Administration of Customs and (SAMR) State Administration of Market Regulation since 2018.
In 2015, a new Catalogue of Hazardous Chemicals was published, which included a list of Extremely Toxic Chemicals.

Administrative authorities: MPS (according to the unchanged 2005 Regulations) and SAWS, which was renamed the Ministry of Emergency Management (MEM) in 2018.
In 2017, a new Pesticide Law was introduced, along with a new List of Restricted Pesticides.

Administrative authority: The Ministry of Agriculture (MOA) took over the work of the NDRC and the MIIT, and was renamed the Ministry of Agriculture and Rural Affairs (MARA) in 2018.

In summary, as of 2025, the production and sale of rodenticides in China is mainly regulated by three regulatory authorities: MARA, MPS and MEM.