Brodifacoum TC ≥ 98% | Bromadiolone TC ≥ 98%

Brodifacoum, Brodifacoum manufacturer in China

BRODIFACOUM TC

Brodifacoum Technical Material, 98% Reg.
MOA’s Reg. No.: PD20070323 (✔)
Extreme Toxic Chemicals Permit (✔)
Restricted Pesticide License (✔)
UN3027, Class 6.1, PG: I. (Steel) (✔)
Legislated Tariff No.: 293220-9011 (✔)
The most potent ‘super-warfarin’ rodenticide, ideal for controlling larger pests, features a complex 8-step synthesis process.

BROMADIOLONE TC

Bromadiolone Technical Material, 98% Reg.
MOA’s Reg. No.: PD20070322 (✔)
Extreme Toxic Chemicals Permit (✔)
Restricted Pesticide License (✔)
UN3027, Class 6.1, PG: I. (Steel) (✔)
Legislated Tariff No.: 293220-9013 (✔)
The most widely used 2nd-generation anticoagulant rodenticide, a 4-step manufactured coumarin derivative.

DIFENACOUM STAGE 6

C₂₂H₂₀O, CAS#56181-66-9, Registration (✔)
Since the 2005 National Industrial Directive (now 2024 edition), China has banned the production of new rodenticide active ingredients, including Difenacoum. We used to have an approved production line for producing some intermediates for export.
Synthesized in the same manner as Brodifacoum without the Bromine in initiation, ecologically safer for birds.

Extremely Toxic Chemicals License since 2002

(now updated to 2015 version: only 2 licensed)

(#2413 Brodifacoum, #2414 Bromadiolone)

Substances exported as “hazardous chemicals” are subject to the supervision of the Maritime Administration – Compliant with “UN3027, Class 6.1, PG: I.”

The “2015 China Directory of Extremely Toxic Chemicals” was compiled based on the list of substances labeled as “剧毒” (Mandarin: Jù Dú, meaning Hyper-Toxic or Extremely Toxic) in the “China Catalogue of Hazardous Chemicals (2015 Edition)” (Current) formulated by the State Administration of Work Safety (SAWS) and other relevant ministries and commissions. Compared to the “2002 Directory of Extremely Toxic Chemicals,” the criteria for determining “Extreme toxicity” have changed. For example, in the 2002 edition of the Directory, the LD₅₀ (rat oral) reference was ≤50 mg/kg, while in the 2015 edition, it has been revised to ≤5 mg/kg.
– the above from https://zh.wikipedia.org/zh-sg/剧毒化学品名录
– Interpretation of the “2015 Catalogue of Hazardous Chemicals” by SAWS:
https://www.mem.gov.cn/gk/zcjd/201503/t20150331_233183.shtml
Brodifacoum (2015 Hazardous Chemicals Number: 2413, labeled as “extremely toxic”) and Bromadiolone (2015 Hazardous Chemicals Number: 2414, labeled as “extremely toxic”) are the highest-level controlled hazardous substances in China. The two main authorities responsible for regulating industrial materials (technical, pure) Brodifacoum and Bromadiolone are the Ministry of Public Security (MPS) and the SAWS (now the Ministry of Emergency Management, abbreviated as MEM). The two regulations in question are the “2005 Measures for the Administration of Permits for the Purchase and Transportation of Extremely Toxic Chemicals” (MPS Order No. 77 of 2005) and the “2011 Regulations on Safe Management of Hazardous Chemicals in China” (State Council Decree 591).
– “MPS Order No. 77 of 2005”:
https://www.gov.cn/zhengce/2021-12/25/content_5712923.htm
– “State Council Decree 591”:
https://www.gov.cn/gongbao/content/2011/content_1825120.htm
On August 19, 2015, the General Office of SAWS issued the “Implementation Guidelines for the List of Hazardous Chemicals (Trial) (2015 Edition)” and attached the “Classification Information Table” for the List.”
– #2313, Bromadiolone, Hazard Category: “Acute toxicity – Oral, Category 1; Acute toxicity – Dermal, Category 1; Acute toxicity – Inhalation, Category 1; Specific target organ toxicity – repeated exposure ‘STOT RE’, Category 1; Hazardous to the aquatic environment, short-term (Acute) ‘Aquatic Acute’- Category Acute 1, Hazardous to the aquatic environment, long-term (Chronic) ‘Aquatic Chronic’ – Category Chronic 1” and labled “Extremely Toxic.”
– #2314, Brodifacoum, Hazard Category: “Acute toxicity – Oral, Category 2*; Acute toxicity – Dermal, Category 1; Acute toxicity – Inhalation, Category 1; Specific target organ toxicity – repeated exposure ‘STOT RE’, Category 1; Hazardous to the aquatic environment, short-term (Acute) ‘Aquatic Acute’- Category Acute 1, Hazardous to the aquatic environment, long-term (Chronic) ‘Aquatic Chronic’ – Category Chronic 1” and labled “Extremely Toxic.”
– SAWS “2015 Implementation Guidelines”:
https://www.mem.gov.cn/gk/gwgg/xgxywj/wxhxp_228/201509/t20150902_232638.shtml
Extremely Toxic License issued by MEM (formerly by SAWS)
Since 2002, in accordance with the regulations on hazardous chemicals, the production and sale of technical (pure) Bromadiolone and Brodifacoum in China have been subject to mandatory hazardous chemical licensing management, reviewed and approved by SAWS. In 2018, this responsibility was assumed by the newly established MEM. In 2021, the relocation of our factory’s new site passed the inspection by the MEM department and obtained an updated license. Currently, only two companies in China have been granted this license, one to us and one to Tianjin.
– Official website for verifying Hazardous Chemical Permits:
– https://whjy.mem.gov.cn/#/licenseSearch
Latest update: Siyang Rodenticide Factory completed the renewal of its new MEM Extremely Toxic Chemical Permit (technical Brodifacoum and Bromadiolone) on 24, June, 2024, which is valid until 23, June, 2027.
– Click to view the license verification results for Siyang Rodenticide Factory.

China’s National Industrial Directive

China has banned new rodenticide manufacturers and new active ingredients since 2005

(Industrial Policy Directory updated to 2024 edition)

On December 2, 2005, China’s national industrial directive officially came into effect. That is, the “Decision of the State Council on Promulgating the ‘Interim Provisions on Promoting Industrial Structure Adjustment’ for Implementation” (Guo Fa [2005] No. 40 of the State Council), which remains in effect today.
– Official link:
https://www.gov.cn/zwgk/2005-12/21/content_133214.htm
In 2005, the National Development and Reform Commission (NDRC) issued the first edition of “Directory for Guiding Industry Restructuring.” This document is a detailed regulatory document based on the 2005 “National Industrial Directive” and is commonly referred to as “National Industrial Policy” in China. Since then, the content of the directory has been adjusted several times in accordance with actual circumstances, with the latest version being the 2024 edition. The directory is divided into three categories: “encouraged,” “restricted,” and “eliminated.” The “Restricted Category” primarily refers to prohibitions on new production capacity, aiming to prevent blind expansion and redundant construction within industries.
Since the directory was first published in 2005, highly toxic pesticides have always been listed as “Restricted Category” up to the current 2024 edition. The directory lists all rodenticides in detail, including “Warfarin, Coumatetralyl, Bromadiolone, and Brodifacoum,” and new production projects involving these substances are prohibited.
China’s restrictions on the rodenticide manufacturing industry (2005 to 2024 version):
– 2005 edition, (Category II: Restricted, Paragraph 4, Section 37)
https://www.ndrc.gov.cn/xxgk/zcfb/fzggwl/200512/t20051222_960679.html
– 2011 edition (Category II: Restricted, Page 66 and 67)
https://www.gov.cn/gzdt/att/att/site1/20110426/001e3741a2cc0f20bacd01.pdf
– 2021 edition (Category II: Restricted, Paragraph 4, Section 8)
https://www.gov.cn/zhengce/2021-12/27/content_5713262.htm
– 2024 edition (Category II: Restricted, Page 88)
https://www.ndrc.gov.cn/xxgk/zcfb/fzggwl/202312/P020231229700886191069.pdf

ICAMA Registration: Brodifacoum Technical 98%

ICAMA Registration: Bromadiolone Technical 98%

Difenacoum Intermediate ≥ 99% | C₂₂H₂₀O

China’s strictest pesticide rodenticide production license

(1997 – 2017)

Brodifacoum and Bromadiolone officially became national pesticides in 2007, and as such pesticides production in China is subject to the issuance of a production license by the AQSIQ, which has been taken over by the MOA since the new pesticide law in 2017.

(only 2 production licenses)

Siyang Rodenticide Factory is a “nationally designated rodenticide” production unit. The term “nationally designated rodenticide” refers to rodenticides that are legally produced, i.e., a technical pesticide rodenticide production enterprise. The production of technical rodenticides in China requires approval from all relevant national ministries and commissions, and a pesticide production license must be obtained before production can commence.
✔ (1) Since the implementation of the Pesticide Management Regulations in China in 1997, rodenticide products, as one category of pesticides, must be registered with the Ministry of Agriculture (MOA).

✔ (2) The production facilities for technical pesticide rodenticides must undergo approval by two minstries. First, the production environment assessment must be approved by the Ministry of Environmental Protection (MEP, now MEE, the Ministry of Ecology and Environment). Second, in accordance with the 2002 Regulations on the Management of Hazardous Chemicals, production safety has been implemented under the SAWS (now MEM) statutory licensing.

✔ (3) The Ministry of Industry and Information Technology (MIIT) verifies the legality of production facilities based on the “2005 National Industrial Directive” issued by the State Council and the “Industrial Policy Directory” of the NDRC, and issues a public announcement. This process is referred to as the “National Designated Pesticide Site.” Finally, enterprises apply to the relevant departments for pesticide production licenses: for General pesticides, they apply to the NDRC for a pesticide license, while for National Standard pesticides, they apply to the General Administration of Quality Supervision, Inspection and Quarantine (AQSIQ) for a pesticide production license (the National Industrial Product Manufacturing License).
Since the national standards for pesticide products Bromadiolone and Brodifacoum were promulgated in 2006, the AQSIQ has only issued two production licenses: one to our company in Siyang and the other to Tianjin.
With the promulgation of the new Pesticide Law in 2017, the MIIT’s “designated site” and the two production license-issuing departments (AQSIQ and NDRC) were fully taken over by the MOA. This marks the completion of the industrial revolution in China’s pesticide industry after more than two decades of development and reform.

The new Pesticide Law of 2017

(Designated site of China’s Restricted pesticides)

New China’s Pesticide Law
On Feb. 8, 2017, the State Council of China approved an amendment to the “Regulation on the Administration of Pesticides” – known as the State Decree No. 677, coinciding with repeal of the 2001 State Decree No. 326.
(https://www.gov.cn/gongbao/content/2017/content_5186961.htm)
List of Restricted Pesticides (2017 Edition)
On August 31, 2017, the Ministry of Agriculture (MOA) of China issued Announcement No. 2567, “List of Restricted-Use Pesticides,” which included a total of 32 pesticides. Among these, 22 pesticides are subject to “designated-site sales,” including four coumarin-based rodenticides: “Warfarin (No. 19), Coumatetralyl (No. 20), Bromadiolone (No. 21), and Brodifacoum (No. 22).”
(http://www.moa.gov.cn/nybgb/2017/dsq/201802/t20180201_6136189.htm)
In 2018, the MOA was officially renamed the Ministry of Agriculture and Rural Affairs (MARA).
February 1, 2019: Siyang Rodenticide Factory passed the new “designated site” of restricted pestides review by the MARA (previously handled by the AQSIQ) and obtained a new restricted pesticide license.
– Latest update: In September 2021, Siyang Rodenticide Factory was relocated and the new site was granted a new MARA’s Restricted Pesticide License (Su) 32000013199, which is valid until 14, Sep. 2026.
(http://nynct.jiangsu.gov.cn/art/2025/3/19/art_80243_11352.html)

New export administration measures updated under

the 2015 Hazardous Chemicals Regulation and the 2017 Pesticides Regulation

The General Administration of Customs (GAC)

The export of pesticides from China is jointly regulated by the MOA and Customs. In China, the statutory tariff number for the pesticide Brodifacoum is “2932209011,” and the statutory tariff number for Bromadiolone is “2932209013.”

In 2018, AQSIQ merged with the newly established State Administration of Market Supervision (SAMR). At the same time, the AQSIQ’s entry-exit inspection and quarantine (well known CIQ, the “China Inspection and Quarantine”) management responsibilities and teams were transferred to the General Administration of Customs (GAC).
(https://en.wikipedia.org/wiki/General_Administration_of_Quality_Supervision,_Inspection_and_Quarantine)
(https://en.wikipedia.org/wiki/State_Administration_for_Market_Regulation)
(http://www.customs.gov.cn/customs/ztzl86/302414/302415/zl70zn_fdxsd/2566516/2585161/index.html)
Dec 18, 2020: The China GAC issued an Announcement No. 129 under the State Council Decree No. 591 (“2011 Hazardous Chemical Regulation”) and the “2015 Hazardous Chemicals List”, repealing AQSIQ Announcement No. 30 of 2012. Mandatory inspection of imports and exports of hazardous chemicals listed in the “2015 Hazardous Chemicals List”, the measures including hazard classification certification, qualified UN GHS labeling and data, UN TDG required packaging, etc. There are 28 pesticides in the new “2015 Hazardous Chemicals List”, including three coumarin-based rodenticides as “Warfarin, Brodifacoum and Bromadiolone”.
(http://www.customs.gov.cn/customs/302249/302266/302267/3476363/index.html)
Dec 31, 2021, In order to implement the obligations of the Rotterdam Convention, the GAC and the MARA jointly issued “Announcement the No. 416” in accordance with the “Chinese Customs Law” and the “Regulation on Pesticide Administration (2017)”.
(http://www.customs.gov.cn/customs/ztzl86/302414/302415/zl70zn_fdxsd/2566516/2585161/index.html)
The implementation of electronic customs clearance for import and export of pesticides. The latest 2022 version of the “Catalogue of the People’s Republic of China for the Administration of the Import and Export of Pesticides” was also released, with the total number of pesticides increased from 1,183 to 1,238. The tariff number for pesticide export number 645, “Brodifacoum,” is 2932209011, and the tariff number for pesticide export number 640, “Bromadiolone,” is 2932209013. These two tariff numbers remain unchanged.
(https://www.gov.cn/zhengce/zhengceku/2021-12/31/5665804/files/a690fececdf44b9aba505e6e40bb19ae.doc)

Siyang Rodenticide Factory is the only licensed exporter of Brodifacoum TC and Bromadiolone TC in China

– based on the 2015 Hazardous Chemicals Regulations and the 2017 Pesticides Act.

Since obtaining export qualifications in 2006, Siyang Rodenticide Factory has been the sole legal exporter of Brodifacoum TC and Bromadiolone TC within China. Currently, the legal procedures for compliant export are as follows (three mandatory certifications):

“Hazard Classification Certificate” – (Certification: Valid only for the current year):
the classification of hazardous chemicals (Bromadiolone TC, Brodifacoum TC) will be certified as “UN3027, Class:6.1, PG: I” with reference to “UN TDG Regulation” (United Nations Recommendations on the Transport of Dangerous Goods – UN Model Regulations, Rev. 23 (2023)).
(Official Link: https://unece.org/transport/dangerous-goods/un-model-regulations-rev-23)
“Syndrome of dangerous package/Dangerous Goods Certificate” – (Certification: The validity period of export packaging is only 12 months):
The export of bromadiolone and brodifacoum is subject to mandatory GAC inspection (formerly CIQ inspection). The certified TDG hazard classification, comply with the provisions of the International Maritime Dangerous Goods Code (IMDG Code), and meet the requirements of the Globally Harmonized System of Classification and Labelling of Chemicals (UN GHS) or the EU CLP (Regulation (EC) No 1272/2008).
(https://www.mem.gov.cn/gk/gwgg/xgxywj/wxhxp_228/201509/t20150902_232638.shtml)
(http://www.customs.gov.cn/customs/ztzl86/302414/302415/zl70zn_fdxsd/2566516/2585161/index.html)
“Pesticide Export Release Certificate” – (Certification: Valid for only 3 months from the date of issuance):
The export release certificate for Chinese pesticides is issued by the MARA, and the export tariffs codes “2932209011 (Brodifacoum)” and “2932209013 (Bromadiolone)” have been included in the relevant Chinese pesticide management regulations (the “Catalogue of the People’s Republic of China for the Administration of the Import and Export of Pesticides,” currently the 2022 edition).
(https://www.gov.cn/zhengce/zhengceku/2021-12/31/5665804/files/a690fececdf44b9aba505e6e40bb19ae.doc)

Siyang Rodenticide Factory

2025: 40th Anniversary

Siyang Rodenticide Factory, as the name implies, is a professional rodenticide manufacturing plant located in Siyang County, China. It was established in March 1985.

A leading pioneer in rodenticides in China, successfully industrializing the synthesis of six anticoagulant rodenticides: “Chlorophacinone, Warfarin, Coumatetralyl, Bromadiolone, Brodifacoum and Difenacoum.”

Under China’s latest regulatory reform in 2017, Siyang Rodenticide Factory is now defined as a “designated site of Restricted-Pesticide” by the MOA for supply of Bromadiolone and Brodifacoum.

Two national rodenticides in China

Brodifacoum, Bromadiolone

In 2005, Siyang Rodenticide Factory participated in the Review Meeting of Rodenticides in China held by the ICAMA (Institute for the Control of Agrochemicals, MOA): Brodifacoum and Bromadiolone were adopted as official rodenticides in China.

In 2006, China SAC and AQSIQ jointly enacted national standards (GB) for Brodifacoum and Bromadiolone, which came into effect in 2007.

Regulatory Reform of Rodenticides in China

In 1985, Siyang Rodenticide Factory was established with the approval of the former Ministry of Chemical Industry.

In 1997, China promulgated its first “Pesticide Management Regulations.”
Regulatory authorities: ICAMA (Institute for the Control of Agrochemicals, MOA).

In 1998, the State Council reorganized its institutions and the Ministry of Chemical Industry was abolished.

In 2002, China promulgated its first “Regulations on the Safety Management of Hazardous Chemicals” and a “List of Extremely Toxic Chemicals.”
Regulatory authorities: (SAWS) the State Administration of Work Safety.

In 2005, China promulgated the National Industrial Directive, along with detailed Industrial Policy Directory.

Regulatory authorities: (NDRC) National Development and Reform Commission
In 2005, the Ministry of Public Security promulgated the Measures for the Administration of Permits for the Purchase and Road Transportation of Extremely Toxic Chemicals.

Regulatory authorities: (MPS) Ministry of Public Security.
In 2007, National Standards (China’s GB) for Bromadiolone and Brodifacoum were introduced.

Regulatory authorities: (AQSIQ) General Administration of Quality Supervision, Inspection and Quarantine.
In 2008, the Ministry of Industry and Information Technology (MIIT) was established to take over some of the responsibilities of the NDRC.
In 2015, a new Catalogue of Hazardous Chemicals was published, which included a list of Extremely Toxic Chemicals.

Regulatory authorities: MPS and SAWS (was renamed the MEM, Ministry of Emergency Management in 2018)
In 2017, a new Pesticide Law was introduced, along with a new List of Restricted Pesticides.

Regulatory authority: The MOA took over the work of the NDRC, the AQSIQ and the MIIT. (was renamed the MARA, the Ministry of Agriculture and Rural Affairs in 2018.)

In summary, as of 2025, the production and sale of rodenticides in China is mainly regulated by three regulatory authorities: MARA, MPS and MEM.