Brodifacoum TC ≥ 98% | Bromadiolone TC ≥ 98%

Brodifacoum, Brodifacoum manufacturer in China

BRODIFACOUM TC

Brodifacoum Technical Material, 98%
UN 3027, Class 6.1, Packing Group: (I)
By law, steel packaging (drums), PG: I
HS: 2932209011 (Legislated in China)
MOA Pesticide Reg. No.: PD20070323
The most potent ‘super-warfarin’ rodenticide, ideal for controlling larger pests, features a complex 8-step synthesis process.

BROMADIOLONE TC

Bromadiolone Technical Material, 98%
UN 3027, Class 6.1, Packing Group: (I)
By law, steel packaging (drums), PG: I
HS: 2932209013 (Legislated in China)
MOA Pesticide Reg. No.: PD20070322
The most widely used 2nd-generation anticoagulant rodenticide, a 4-step manufactured coumarin derivative.

DIFENACOUM STAGE 6

Synthesized in the same manner as Brodifacoum without the Bromine in initiation, ecologically safer for birds.
C₂₂H₂₀O (CAS# 56181-66-9), Purity ≥ 99.7%
According to the 2005 Industrial Decree, the production of new rodenticide is prohibited in China. The evaluated Difenacoum line is therefore only licensed to produce some intermediates to meet overseas demand.

Legal Hazardous Substance Licenses in China since 2002

(now updated to 2015 version)

(#2413 Brodifacoum, #2414 Bromadiolone – China Dangerous Goods Code)

Substances exported as hazardous chemicals are subject to the supervision of the Maritime Administration – (UN 3027, Class 6.1, PG: I)

2011 National Legislation: Hazardous Chemical Regulation
The “Regulation on the Safety Management of Hazardous Chemicals”, as revised, was adopted at the 144th executive meeting of the State Council on February 16, 2011, which is hereby promulgated, and shall come into force on December 1, 2011. by Premier: Wen Jiabao, on March 2, 2011. – known as the State Council Order No. 591, coinciding with repeal of the 2002 State Council Order No. 344, by Premier Zhu Rongji, on Jan.26, 2002.
2015 Regulation-based Catalogs: “List of Jù Dú* Chemicals (2015)” was promulgated under the new 2011 Hazardous Chemical Regulation. (*”Jù Dú”, Mandarin, meaning hyper-toxic, extremely toxic or very toxic, usually GHS Acute Toxicity Category 1). And the criteria for China’s “Jù Dú” determination are: 2015 Edition by “Rat Oral LD₅₀≤5mg/kg, Dermal LD₅₀≤50mg/kg”, with a total of 148 substances, while repealing the 2002 Edition “Rat Oral LD₅₀≤50mg/kg, Dermal LD₅₀≤200mg/kg”.
– On February 27, 2015, ten (10) Chinese national ministries and commissions jointly released the new “Catalog of Hazardous Chemicals (2015)”, which is contains a “List of Dù Dú chemicals (2015)”. The “Catalog of Hazardous Chemicals (2002)”, (SAWS Order No.1, 2003) and the “List of Jù Dú Chemicals (2002)”, (Announcement No.2, 2003 of Eight Ministries including SAWS) shall be repealed hereby.
– The chemical substances, “3-[3-(4′-bromobiphenyl-4-yl)-1,2,3,4-tetrahydro-1-naphthyl]-4-hydroxycoumarin” (commodity name/pesticide: Brodifacoum) with a Hazardous List Number of 2413 (Jù Dú), and “3-[3-(4′-bromo[1,1′-biphenyl]-4-yl)-3-hydroxy-1-phenylpropyl]-4-hydroxy-2-benzopyrone” (commodity name/pesticide: Bromadiolone), with a Hazardous List Number of 2414 (Jù Dú), are the highest-ranking controlled hazardous substances in China, with the Ministry of Emergency Management (MEM) (formerly SAWS, the State Administration of Work Safety) and the Ministry of Public Security (by the “Measures for the Administration of Licenses for the Purchase and Road Transportation of Jù Dú Chemicals in China (2005)” – Order 77 of the Ministry of Public Security) as the main regulatory authorities.
– In Sept 2015, SAWS issued a guidance document containing official GHS classifications for chemicals in the Catalogue.
The above regulations establish a much tighter regulatory regime for Jù Dú chemical than regular hazardous chemicals in China and set additional requirements on the storage, purchase and sales of Jù Dú chemicals. This area is mainly regulated by the public security authorities.
2018 – New License issued by MEM (former SAWS Hazardous License)
– Bromadiolone and Brodifacoum have been subject to a mandatory hazardous chemical license since 2002 under the above rules and regulations. Until the SAWS was merged into the newly created MEM (Ministry of Emergency Management) in 2018, Siyang Rodenticide Factory had gone through five renewals since it was first licensed in 2003. Our new 2021 relocation site passed MEM inspection and was issued updated Hazardous Chemicals licenses for Brodifacoum Technical materail and Bromadiolone Technicacl material. (https://www.mem.gov.cn/gk/gwgg/xgxywj/wxhxp_228/201509/t20150902_232638.shtml)
– LATEST UPDATE: Siyang Rodenticide Factory completed the renewal of its new MEM Hazardous Chemical Permit (the Hazardous Chemcials # 2413, #2414, (Brodifacoum, Bromadiolone)) on 24/JUNE/2024, which is valid until 23/JUNE/2027.

Since 2005, China enacted a ‘National Industrial Decree’

banning all new rodenticide products and new players

(now updated to 2024 edition)

Dec. 2, 2005, China’s National Industrial Regulations launched – the Decision of the State Council on Promulgating the “Interim Provisions on Promoting Industrial Structure Adjustment” for Implementation (the No. 40 [2005] of the State Council).
– According to the “Directory for Guiding Industry Restructuring (2005)” (now updated to 2024 edition)”, which is a detailed catalog directive to the “Provisions on Promotion Industrial Restructure Adjustment”, new production of highly toxic pesticides is prohibited in China, including all registered rodenticides involved in the list of “Zinc phosphide, Aluminum Phosphide, Diphacinone, Chlorophacinone, Warfarin, Coumatetralyl, Bromadiolone, Brodifacoum.” (https://www.ndrc.gov.cn/xxgk/zcfb/fzggwl/200512/t20051222_960679.html)
On December 12, 2006, the Ministry of Land and Resources of the People’s Republic of China (now Ministry of Natural Resources) and the National Development and Reform Commission of the People’s Republic of China (NDRC) jointly issued the “Catalogue of Prohibited Land Use Projects (2006 version)”. Land use approvals for new, reconstruction and expansion highly toxic pesticide technical production are prohibited. (including all rodenticides in China, zinc phosphide, Warfarin, Coumatetralyl, Bromadiolone, Brodifacoum). (https://www.gov.cn/zwgk/2006-12/18/content_471717.htm)
Currently updated to the 2012 edition.
– LATEST UPDATE: Order of NDRC, the National Development and Reform Commission of the People’s Republic of China (Order No. 7), the “Catalogue for Guiding Industry Restructuring (2024 Version)”, as deliberated and approved at the 6th executive meeting on December 1, 2023, is hereby issued, and shall come into force on February 1, 2024, upon which the “Catalogue for Guiding Industry Restructuring (2019 Version)” is repealed. Zheng Shanjie, Chairman, December 27, 2023.
(https://www.ndrc.gov.cn/xxgk/zcfb/fzggwl/202312/t20231229_1362999.html) – Page 88, Prohibition of highly toxic pesticides, list of rodenticides: Warfarin, Coumatetralyl, Bromadiolone, Brodifacoum, etc.

ICAMA Registration: Brodifacoum Technical 98%

ICAMA Registration: Bromadiolone Technical 98%

Difenacoum Intermediate ≥ 99% | C₂₂H₂₀O

China Legal Production Qualification of Pesticide Rodenticides (1997 – 2017)

In China it is complicated and can simply be understood as European Regulation (EU) No 528/2012 replacing Directive 98/8/ec. The only rodenticides in the Chinese “EU Article 95 List” are Brodifacoum and Bromadiolone, and there are only two legalized units in China, i.e. Siyang and Tianjin.

(Brodifacoum and Bromadiolone officially became National Rodenticides in 2007, and as such production in China is subject to the issuance of a production license by the AQSIQ, which has been taken over by the MOA since the new pesticide law in 2017.)

Substances export are as pesticides are subject to the supervision of the MOA Administration (Commodity codes legislated: 2932209011/13).

Siyang Rodenticide Factory is State – “Designated-Site Rodenticide Plant”. The “designated-site”, a direct translation from Mandarin, in fact, it refers to the pesticide rodenticide that is really produced in China with full qualification, which is approved by three ministries and commissions in turn, and ultimately obtains the AQSIQ production license:
✔ (1) First of all, since 1997, China’s pesticide management regulations are implemented, rodenticide as a commercial pesticide must be registered in the MOA;
✔ (2) Secondly, as a manufacturer of pesticide technical materials, the environmental and safety evaluation of its production sites needs to be reviewed and approved by NDRC, the National Development and Reform Commission.
✔ (3) Since the implementation of the national standards for Brodifacoum and Bromadiolone in 2007, rodenticides have become official pesticide products at the national level. So after completing the above two qualifications, the final authorization of production permit is carried out by AQSIQ, the General Administration of Quality Supervision, Inspection and Quarantine of the People’s Republic of China.
✔ China’s AQSIQ finally approved the production of two rodenticide active ingredients, Brodifacoum and Bromadiolone, by two production sites designated by the National Development and Reform Commission (NDRC) as complying with national standards.
Since 2008, the renewal of NDRC-designated production sites has been taken over by the Ministry of Industry and Information Technology (MIIT). This is because the NDRC banned new production sites after 2005 and they have completed their historical mission of approving the production of rodenticides in China.
From 2017, under the new pesticide law, MOA took over the renewal of designated sites from the Ministry of Industry and Information Technology (MIIT), and also took over the renewal of production certificates from AQSIQ (now State Administration for Market Regulation). It also marks the completion of China’s pesticide industrial revolution after more than two decades of development and reform.

– In 2017, China’s NEW pesticide law and regulations

Regulation on Pesticide Administration (first in 1997, then 2001 and now 2017)
On Feb. 8, 2017, the State Council of China approved an amendment to the “Regulation on the Administration of Pesticides” – known as the State Decree No. 677, coinciding with repeal of the 2001 State Decree No. 326.
Rules of the Regulation (Ministerial Regulation, MOA Proclamation No. 2567)
On August 31, 2017, China’s Ministry of Agriculture (MOA) issued Proclamation No. 2567, the “List of Restricted Use Pesticides,” in which a total of 32 pesticides were included, covering all eight rodenticides that are in active registration status in China, “Type C Botulinum, Type D Botulinum, Flocoumafen, Diphacinone sodium, Warfarin, Coumatetralyl, Bromadiolone and Brodifacoum.”
According to MOA No. 2567 regulation, rodenticides have been classified as restricted pesticides in China and will be subject to designation marketing management, re-planned and designated sales sites, and a new restricted license issued by the state, as well as a requirement for ID-verified at the time of purchase.
Feb. 1, 2019: Siyang Rodenticide Factory obtained a new restricted pesticide license by MOA (former AQSIQ license), which is a national electronic disclosure of pesticide data with QR code scanning management, and the active ingredient of rodenticide produced in China with authenticity and traceability.
– LATEST UPDATE: In September 2021, Siyang Rodenticide Factory was relocated and the new site was granted a new MOA Restricted Pesticide License (Su) 32000013199, which is valid until 14/Sep./2026.

Export controls updated under the Hazardous Chemicals Regulations 2015 and the Pesticides Act 2017

The General Administration of Customs (GAC)

In 2018, AQSIQ merged with the newly established State Administration of Market Supervision. At the same time, the AQSIQ’s entry-exit inspection and quarantine (well known CIQ, the “China Inspection and Quarantine”) management responsibilities and teams were transferred to the General Administration of Customs (GAC).
Dec 18, 2020: The China GAC issued an Announcement No. 129 under the State Council Decree No. 591 (“2011 Hazardous Chemical Regulation”) and the “2015 Hazardous Chemicals List”, repealing AQSIQ Announcement No. 30 of 2012. Mandatory inspection of imports and exports of hazardous chemicals listed in the “2015 Hazardous Chemicals List”, the measures including hazard classification certification, qualified UN GHS labeling and data, UN TDG required packaging, etc. There are 28 pesticides in the new “2015 Hazardous Chemicals List”, including three coumarin-based rodenticides as “Warfarin, Brodifacoum and Bromadiolone”.
Dec 31, 2021, In order to implement the obligations of the Rotterdam Convention, the GAC and the MOA jointly issued “Announcement the No. 416” in accordance with the “Chinese Customs Law” and the “Regulation on Pesticide Administration (2017)”.
The implementation of electronic customs clearance for import and export of pesticides. The latest 2022 version of the “Catalogue of the People’s Republic of China for the Administration of the Import and Export of Pesticides” was also released, with the total number of pesticides increased from 1,183 to 1,238. The pesticide export number for “Brodifacoum is 2932209011″ and the pesticide export number for “Bromadiolone is 2932209013″, which remain unchanged.

Siyang Rodenticide Factory is the exclusive licensed exporter of Brodifacoum TC and Bromadiolone TC in China

– based on the Hazardous Chemicals Regulations and the Pesticides Act.

Siyang Rodenticide Factory is the exclusive licensed exporter of Brodifacoum TC and Bromadiolone TC in China since 2006 and the current legal procedures for export are as follows (three mandatory certifications):

“Hazard Classification Certificate” – (Valid for current year):
the classification of hazardous chemicals (Bromadiolone TC, Brodifacoum TC) will be certified as “UN3027, Class:6.1, PG: I” with reference to “UN TDG regulation” (United Nations Recommendations on the Transport of Dangerous Goods – UN Model Regulations, now in its 23nd revised edition of 2023); Official Link: https://unece.org/transport/dangerous-goods/un-model-regulations-rev-23
“Syndrome of dangerous package/Dangerous Goods Certificate” – (Valid for 12 months):
the above classified UN packaging (UN 3027, Class 6.1, PG : I) is subject to a mandatory Customs GAC inspection (formerly CIQ insepction) under the the International Maritime Dangerous Goods Code (IMDG Code) in order to comply with the TDG-Certified, the UN GHS (Globally Harmonized System of Classification and Labelling of Chemicals) or EU CLP (Regulation (EC) No 1272/2008);
“Pesticide Export Release Certificate” – (Valid for 3 months):
In accordance with the Rotterdam Convention, the export release order for Chinese pesticides is issued by MOA, and its Export Commodity Codes “2932209011 (Brodifacoum)” and “2932209012 (Bromadiolone)” has been included in the relevant regulations on pesticide management in China (Catalogue of the People’s Republic of China for the Administration of the Import and Export of Pesticides, now 2022 edition).

Siyang Rodenticide Factory – (40th anniversary)

Siyang Rodenticide Factory, as the name implies, is a professional rodenticide manufacturing plant located in Siyang County, China. It was established in March 1985 as a collectively owned enterprise.

Siyang Rodenticide Factory is the pioneer of rodenticides in China and has been involved in the development of a total of six anticoagulant rodenticides in the past decades, “Chlorophacinone, Warfarin, Coumatetralyl, Bromadiolone, Brodifacoum and Difenacoum.”

Under China’s latest regulatory reform, Siyang Rodenticide Factory is now defined as a “Restricted Pesticide Site designated by the MOA” for supply of Technical Bromadiolone and Brodifacoum.

National rodenticides identified in China

In 2005, Siyang Rodenticide Factory participated in the Review Meeting of Rodenticides in China held by the ICAMA (Institute for the Control of Agrochemicals, MOA): Brodifacoum and Bromadiolone were adopted as official rodenticides in China.

In 2006, China SAC and AQSIQ (General Administration of Quality Supervision, Inspection and Quarantine of China) jointly enacted national standards for Brodifacoum and Bromadiolone, which came into effect in 2007.

Points of reforms and changes in rodenticide administration in China (2005 – 2024)

2005: National industrial decree bans new rodenticide players; 2007: National Standards for Brodifacoum and Bromadiolone (AQSIQ production license); 2017: New pesticide laws (MOA’s Restricted Pesticide License); 2023: Pesticide registration regulations (draft), the registration will not be renewed without a production license.

In 2008, the AQSIQ officially authorized and issued the “Manufacturing Permit of National Industrial Product” to the Siyang Rodenticide Factory for national standards Brodifacoum and Bromadiolone. In China, only two manufacturers have been officially approved by the state for production licenses.
In 2013, Siyang Rodenticide Factory obtained a five-year renewal of the “AQSIQ authorisation permit” for the production of Technical Brodifacoum and Brodifacoum, as well as the processing of 0.5% TK (the national standard for concentrates in China is set at 0.5%, with no other concentration).
In 2018, the AQSIQ was merged with the newly created State Administration for Market Regulation. According to the new pesticide laws and regulations in 2017, Siyang Rodenticide Factory was granted a new state pesticide license (restricted) by the MOA in 2019, No. (SU) 32000010534.
In 2021, the extremely toxic chemical storage facility at the new site of Siyang Rodenticide Factory first passed the security permit of MEM, then the warehouse was relocated, and finally the new plant again passed the inspection of “MOA’s Restricted Pesticide Site” and was issued a new permit (SU) 32000013199.
In 2024, Siyang Rodenticide Factory completed the renewal of its new MEM hazardous chemicals license (Extremely Toxic Chemicals: Brodifacoum TC and Bromadiolone TC), which is valid until 23 June 2027.